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Dr. Abagail Tyler is played by Milla Jovovich. Tyler is a psychiatrist in Nome, Alaska and studies the sleep deprived patients of Nome. She is the main character of the story and very much the enabler to the action.

Ashley Tyler is played by Mia McKenna-Bruce. Ashley is Dr. Tyler's daughter.

Robbie Tyler is played by Raphael Coleman. Robbie is Dr. Tyler's son.

Tommy Fisher is played by Corey Johnson. Fisher is one of Abagail Tyler's patients that she hypnotizes.

Abel Campos is played by Elias Koteas. Campos is Tyler's colleague that attempts to deduce the cause of the horror in Tyler's patients.
Sheriff August is played by Will Patton. August is Dr. Tyler's foil, firmly disbelieving Tyler's claims of alien abduction.
Awolowa Odusami is played by Hakim Kae-Kazim. Odusami is the expert called on by Dr. Tyler to interpret the language of her patients while under hypnosis.
Scott Stracinsky is played by Enzo Cilenti. Stracinsky is another patient of Tyler's and becomes paralyzed as a result of Tyler's hypnosis.

 

The picture of Mia McKenna-Bruce is compliments of bbc.co.uk